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胡永红
发布时间:2017-04-18
胡永红
博士
教授
硕士研究生导师
联系电话:0311-80787500
电子邮件:yonghong79@163.com
所属专业:生态学
学习经历:
2008年,中国科学院动物研究所,博士研究生毕业,获得理学博士学位
2005年,williamhill中国官方网站,硕士研究生毕业,获得理学硕士学位
2002年,williamhill中国官方网站,本科毕业,获得理学学士学位
主要教学、科研工作:
教学方面,主讲本科生《生物化学》、《生物化学实验》、《生理生态学实验》等课程。指导大学生科技创新项目2项,创新能力训练计划项目2项。主持校级教改课题1项。
科研方面,从事蜱类生理生态与分子生态学研究。蜱类是专性吸血的外寄生动物,传播病毒、立克次体、细菌、螺旋体、原虫等多种病原体而导致疾病,给人类健康、畜牧业和野生动物带来极大危害。课题组主要以长角血蜱为研究对象,研究方向包括:(1)利用生物化学、分子生物学、免疫学等研究方法,从蜱体内筛选出具有免疫原性的保护性抗原,通过免疫接种动物实验鉴定其免疫功能;(2)通过Pull down、酵母双杂、转录组等研究技术,解析蜱对宿主IgG的免疫逃避策略。研究结果为制备抗蜱疫苗提供依据,对于揭示蜱类免疫应答机制以及蜱类防治具有重要的理论意义和实际应用价值。目前已指导毕业硕士研究生16名,在读硕士研究生5名。
承担的科研项目:
1. 主持国家自然科学基金面上项目(32370506),2024-2027
2. 主持国家自然科学基金青年项目(31402022),2015-2017
3. 主持国家教育部“春晖”计划科研合作项目(Z2017018),2018-2019
4. 主持国家教育部高等学校博士学科点基金(20131303120008),2014-2016
5. 主持第55批中国博士后科学基金(2014M551042),2014-2015
6. 主持河北省自然科学基金面上项目(C2021205010),2021-2023
7. 主持河北省自然科学基金面上项目(C2015205126),2015-2018
8. 主持河北省自然科学基金青年项目(C2011205104),2011-2013
9. 主持河北省教育厅自然科学基金(2011160),2012-2014
10. 主持williamhill中国官方网站重点基金(L2020Z06),2020-2022
11. 主持williamhill中国官方网站重点基金(L2012Z06),2013-2015
12. 主持williamhill中国官方网站博士基金(L2008B10),2009-2011
发表的论文:
1. Wang D., Li R., Wu Y. X., Fan X. Y., Liu X. Y., Yang F., Zhang T. T., Ma J. Y., Hu Y. H*. Molecular characterization of hexokinase (HK) in Haemaphysalis longicornis and evaluation of HK protein- and DNA-based vaccines against adult ticks. Pest Management Science, 2023; 79(5): 1721–1730.
2. Cao Y. Y., Xiao S. W., Yang F., Liu X. Y., Lu H., Zhang J. C., Hu Y. H*. Molecular characterization and immune efficacy of fructose-1,6-bisphosphate aldolase from Haemaphysalis longicornis (Acari: Ixodidae). Parasites & Vectors, 2023; 16(1):169.
3. Liang N., Dong H. M., Fan X. Y., Wu Y. X., Yang F., Liu X. Y., Hu Y. H*. Characterization and evaluation of a new triosephosphate isomerase homologue from Haemaphysalis longicornis as a candidate vaccine against tick infection. Ticks and Tick-borne Diseases, 2022, 13(4):101968.
4. Fan X. Y., Xu X. C., Wu Y. X., Liu X. Y., Yang F., Hu Y. H*. Evaluation of anti-tick efficiency in rabbits induced by DNA vaccines encoding Haemaphysalis longicornis lipocalin homologue. Medical and Veterinary Entomology, 2022, 36(4):511–515.
5. Wang D., Cao Y. Y., Wu Y. X., Fan X. Y., Wang F. Hu Y. H*. Characterization of fructose-1, 6-bisphosphate aldolase in Dermacentor silvarum. International Journal of Acarology, 2021, 47(8): 708–713.
6. Wang D., Xu X. C., Lv L. H., Wu P. X., Dong H. M., Xiao S. W., Liu J. Z*, Hu Y. H*. Gene cloning, analysis and effect of a new lipocalin homologue from Haemaphysalis longicornis as a protective antigen for an anti-tick vaccine. Veterinary Parasitology, 2021, 290: 109358.
7. Wu P. X., Cui X. J., Cao M. X., Lv L. H., Dong H. M., Xiao S. W., Liu J. Z.*, Hu Y. H*. Evaluation on two types of paramyosin vaccines for the control of Haemaphysalis longicornis infestations in rabbits. Parasites & Vectors, 2021, 14(1):309.
8. Wang D., Zhao X. H., Cui Y., Zhang T. T., Wang F., Hu Y. H*. Efficacy and safety of Tripterygium wilfordii Hook F for CKD in mainland China: A systematic review and meta-analysis. Phytotherapy Research, 2018, 32: 436-451.
9. Wang F., Wang D., Jiang C. Z., Liang N., Hu Y. H.*, Liu J. Z*. Morphology and ultrastructure changes of Haemaphysalis longicornis Neumann (Acari: Ixodidae) female adult ticks at different developmental stages. International Journal of Acarology, 2017, 43(4): 308–313.
10. Zhang T. T., Zhang J. C., Cui X. J., Zheng J. J., Li R., Wang F., Liu J. Z.*, Hu Y. H*. Evaluation of immune protection induced by DNA vaccines from Haemaphysalis longicornis paramyosin in rabbits. Parasites & Vectors, 2017, 10: 325.
11. Zhang T. T., Cui X. J., Zhang J. C.,Wang H., Wu M., Zeng H., Cao Y. Y., Liu J. Z.*, Hu Y. H*. Screening and identification of antigenic proteins from the hard tick, Dermacentor silvarum (Acari: Ixodidae). Korean Journal of Parasitology, 2015, 53 (6): 789-793.
12. Hu Y. H.#, Zeng H. #, Zhang J. C., Wang D., Li D. M., Zhang T. T., Yang S. J., Liu J. Z. Gene cloning, expression and immunogenicity of the protective antigen subolesin in Dermacentor silvarum. Korean Journal of Parasitology, 2014, 52 (1): 93-97.
13. Hu Y. H., Zhang J. C., Yang S. J., WangH., Zeng H., Zhang T. T., Liu J. Z. Screening and molecular cloning of a protective antigen from the midgut of Haemaphysalis longicornis. Korean Journal of Parasitology, 2013, 51 (3): 327-334.
14. Tang Q. B.#, Hu Y. H.#, Kang L., Wang C. Z. Characterization of glucose-induced glucose oxidase gene and protein expression in Helicoverpa armigera larvae. Archives of Insect Biochemistry and Physiology, 2012, 79 (1): 104-119.
15. Hu Y. H., Leung D. W. M., Kang L., Wang C. Z. Diet factors responsible for the change of the glucose oxidase activity in labial salivary glands of Helicoverpa armigera. Archives of Insect Biochemistry and Physiology, 2008, 68 (2): 113-121.